Aptagen, LLC
#71T (ID# 9537)
DNA
BACE1
Small Organic
10.3±3.7 nM (reported value)
78.8°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dGpdCpdCpdTpdGpdTpdTpdGpdTpdGpdApdGpdCpdCpdTpdCpdCpdTpdApdApdCpdGpdGpdCpdGpdTpdApdGpdGpdGpdTpdTpdTpdGpdTpdTpdGpdTpdCpdTpdCpdTpdApdTpdTpdTpdCpdTpdTpdTpdGpdTpdApdTpdTpdGpdTpdGpdTpdTpdGpdTpdGpdTpdTpdCpdGpdCpdTpdTpdApdTpdTpdCpdTpdTpdGpdTpdCpdTpdCpdCpdCp-3'
89
27308.6 g/mole
792200 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Gasse C, M Zaarour, S Noppen, M Abramov, P Marlie`re, S Liekens, B De Strooper and P Herdewijn. (2018). Modulation of BACE1 activity by chemically modified aptamers. ChemBioChem 19:754–763. DOI: 10.1002/cbic.201700461
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