Aptagen, LLC
12Rd-5 Aptamer for Tris(bipyridine) Ruthenium(II), Tu(bpy)3 2+ (ID# 8561)
RNA
Tris(bipyridine) Ruthenium(II), Ru(bpy)3 2+
Small Organic
65 nM (reported value)
20mM HEPES, 100mM NaCl, and 5mM MgCl2 (pH 7.0) @ 4°C
84.4°C°C
85 °C for 10 min, followed by cooling at 4 °C
The aptamer bound one enantiomer, Λ-Ru(bpy)3 2+, but not the other, Δ-Ru(bpy)3 2+.
A truncated version of the sequence from A9 to U58 was also found to recognize the target.
5'-rGprGprGprAprCprAprCprAprAprUprGprGprAprCprGprAprUprCprAprUprAprUprAprAprCprGprAprUprAprGprCprAprCprUprGprGprCprGprUprAprGprGprGprAprGprAprCprUprAprCprGprUprGprUprCprCprGprUprGprUprGprUprAprCprCprUprAprAprCprGprGprCprCprGprAprCprAprUprGprAprGprAp-3'
82
26555 g/mole
832700 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Thoa, T., Minagawa, N., Aigaki, T., Ito, Y., and Uzawa, T. Regulation of photosensitisation processes by an RNA aptamer. Sci Rep 7, 43272 (2017). https://doi.org/10.1038/srep43272
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