Aptamer Details
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MCP-1 (ADR7) (ID# 46)
* The secondary structure may not be accurate because of
MFOLD limitations on chemistries other than RNA/DNA.
* The secondary structure may not be accurate because of
MFOLD limitations on chemistries other than RNA/DNA.
- Aptamer Chemistry
- 2'-F-RNA
- Target
- Monocyte chemoattractant protein-1 (mouse)
- Antigen/Target Category
- Protein
- Affinity (Kd)
- 180 pM (reported value)
- Binding Conditions/Buffer
- Selection Buffer (110 mM NaCl, 1 mM MgCl2, 20 mM HEPES (pH 7.0), 1 mM CaCl2, 5 mM KCl, 0.001% HSA, 0.05% Tween 20)
- Binding Temp
- 37 °C
- Refolding Protocol
- None given.
- Sequence ( )
-
5'--3'
- Length
- 70
- Molecular Weight
- 22580.5 g/mole
- Extinction Coefficient
- 670700 L/(mole·cm)
- Reference
-
Rhodes, Andrew, et al. "The generation and characterisation of antagonist RNA aptamers to MCP-1." FEBS Letter, 506 (2001): 85-90.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Have your aptamer oligo or peptide synthesized.
Related Aptamer Targets
There are no aptamers related to this aptamer.
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