Aptamer Details
- Aptamer Chemistry
- DNA
- Target
- Ethanolamine
- Antigen/Target Category
- Small Organic
- Affinity (Kd)
- 6 nM (reported value)
- Binding Conditions/Buffer
- Binding Buffer (100 mM NaCl, 20 mM Tris/HCl (pH 7.6), 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% Tween 20).
- Binding Temp
- 21 °C
- Refolding Protocol
-
NA
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
- Sequence ( )
-
5'--3'
- Length
- 96
- Molecular Weight
- 29786.42 g/mole
- Extinction Coefficient
- 940500 L/(mole·cm)
- Reference
-
Mann, Doerthe, et al. "In vitro selection of DNA aptamers binding ethanolamine." Biochemical and Biophysical Research Communication, 338 (2005): 1928-1934. Tradmarked in patent, "New DNA aptamers specific for compunds that contain the ethylamino group, useful for diagnosis, prevention and treatment of ethanolaminosis, schizophrenia and neurodegeneration (Original document: DE 102005052275 (B4))"
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Related Aptamer Targets
There are no aptamers related to this aptamer.
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