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Apta-Index™: Neomycin B Aptamer (ID# 651)

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Neomycin B Aptamer (ID# 651)

Neomycin B Aptamer
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-O-Me-RNA Neomycin B Small Organic 1.24-2.5 nM (reported value) The binding buffer used was 50mM TRIS/HCl pH 7.4 containing 250mM NaCl and 5mM MgCl2 N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Noemí de-los-Santos-Álvarez, María Jesús Lobo-Castañón, Arturo J. Miranda-Ordieres, Paulino Tuñón-Blanco, SPR sensing of small molecules with modified RNA aptamers: Detection of neomycin B, Biosensors and Bioelectronics, Volume 24, Issue 8, 2009, Pages 2547-2553

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