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Apta-Index™: A1-949 (ID# 648)

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A1-949 (ID# 648)

A1-949
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Histamine Small Organic 0.37 µM (reported value) 50 mM HEPES pH 7.0,250 mM NaCl, 2 mM glycine N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dTpdApdCpdGpdApdTpdCpdCpdApdGpdTpdGpdGpdGpdTpdTpdGpdApdApdGpdGpdApdApdApdGpdTpdApdApdCpdApdGpdApdTpdCpdGpdTpdAp-3'
37

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Dwidar, M., Seike, Y., Kobori, S., Whitaker, C., Matsuura, T., & Yokobayashi, Y. (2019). Programmable Artificial Cells Using Histamine-Responsive Synthetic Riboswitch. Journal of the American Chemical Society.

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