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Apta-Index™: B23 LH aptamer (ID# 644)

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B23 LH aptamer (ID# 644)

B23 LH aptamer
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA luteinising hormone Protein 321 nM (reported value) PBS N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Predicted to form a G-quadruplex.
5'-dTpdApdTpdGpdGpdTpdApdTpdGpdCpdTpdGpdTpdGpdTpdGpdGpdTpdApdTpdGpdGpdGpdGpdTpdGpdGpdCpdGpdTpdGpdCpdTpdCpdTp-3'
35

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Liang S, Kinghorn AB, Voliotis M, et al. Measuring luteinising hormone pulsatility with a robotic aptamer-enabled electrochemical reader. Nat Commun. 2019;10(1):852. Published 2019 Feb 20. doi:10.1038/s41467-019-08799-6

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