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Apta-Index™: 5TRG2 (ID# 635)

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5TRG2 (ID# 635)

5TRG2
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA MUC1-5TR-GalNAc; Tn antigen Protein 18.6 nM (reported value) 150 nM NaCl, 5nM MgCl2, pH 7.4 Refolded in binding conditions Target is O-linked glycan-peptide specific to epithelial cancer cells. Sequence is 5'-dGpdApdGpdApdCpdApdApdGpdApdApdTpdApdApdApdCpdGpdCpdTpdCpdApdApdGpdGpdCpdTpdApdTpdApdGpdCpdApdCpdApdTpdGpdGpdGpdTpdApdApdApdApdCpdGpdApdCpdTpdTpdCpdGpdApdCpdApdGpdGpdApdGpdGpdCpdTpdCpdApdCpdApdApdCpdApdGpdGpdCp-3'
5'-dGpdApdGpdApdCpdApdApdGpdApdApdTpdApdApdApdCpdGpdCpdTpdCpdApdApdGpdGpdCpdTpdApdTpdApdGpdCpdApdCpdApdTpdGpdGpdGpdTpdApdApdApdApdCpdGpdApdCpdTpdTpdCpdGpdApdCpdApdGpdGpdApdGpdGpdCpdTpdCpdApdCpdApdApdCpdApdGpdGpdCp-3'
70

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Ferreira, C.S.; Cheung, M.C.; Missailidis, S.; Bisland, S.; Gariepy, J. Phototoxic aptamers selectively enter and kill epithelial cancer cells. Nucleic acids research 2009, 37, 866-876.

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