Aptagen, LLC
DNA
peptidoglycan
Other
268.5 nM (reported value)
Selection buffer (PBS containing 1.4 mM MgCl2 and 0.05% BSA); Room temperature (45 mins)
°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Antibac 1 was tested on the strains A. baumanni, L. monocitogenes, E. coli, S. aureus, and K. pneumonia, among others. The Kd listed above is for A. baumanni.
Antibac1 (ID# 624)
5'dTpdCpdGpdCpdGpdCpdGpdApdGpdTpdCpdGpdTpdCpdTpdGpdGpdGpdGpdApdCpdApdGpdGpdGpdApdGpdTpdGpdCpdGpdCpdTpdGpdCpdTpdCpdCpdCpdCpdCpdCpdGpdCpdApdTpdCpdGpdTpdCpdCpdTpdCpdCpdCp3'
55
16833.83 g/mole
486900 L/(mole·cm)
72.73%
2.05
34.57
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
A Graziani et al. High efficiency binding aptamers for a wide range of sepsis 1 bacterial agents. JMB Papers in Press. 2017: JMB16-11004.
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