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Apta-Index™: Insulin Binding Aptamer (IBA) (ID# 608)

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Insulin Binding Aptamer (IBA) (ID# 608)

Insulin Binding Aptamer (IBA)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Insulin Protein n/a nM (reported value) 50 mM Tris-HCl, 10 mM KCl, 100 mM NaCl N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. FAM-Labeled at 3' end.
5'-dGpdGpdTpdGpdGpdTpdGpdGpdGpdGpdGpdGpdGpdGpdTpdTpdGpdGpdTpdApdGpdGpdGpdTpdGpdTpdCpdTpdTpdCp-3'
30 9493.19 g/mole 288200.00 L/(mole·cm) 66.67% 3.47 32.94

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Pu, Y.; Zhu, Z.; Han, D.; Liu, H.; Liu, J.; Liao, J.; Zhang, K.; & Tan, W. Insulin-Binding Aptamer-Conjugated Graphene Oxide for Insulin Detection. Analyst, 2011, 136, 4138-4140

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