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Apta-Index™: NaA43 (ID# 603)

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NaA43 (ID# 603)

NaA43
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Sodium Ion Other 39.1 mM (reported value) Dulbecco’s modification of Eagle’s medium (DMEM) supplemented with 10% Fetal Bovine Serum (FBS), 100 U/mL penicillin, and 100 µg/mL streptomycin, N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. SUBSTRATE SEQUENCE (spaces added before and after the ribonucleic A): dCpdTpdCpdTpdApdTpdGpdTpdApdTp rAp dGpdGpdApdApdGpdTpdApdCpdCpdGpdCpdCpdGpdCp
5'-dGpdCpdGpdGpdCpdGpdGpdTpdApdCpdCpdApdGpdGpdTpdCpdApdApdApdGpdGpdTpdGpdGpdGpdTpdGpdApdGpdGpdGpdGpdApdCpdGpdCpdCpdApdApdGpdApdGpdTpdCpdCpdCpdCpdGpdCpdGpdGpdTpdTpdApdCpdApdTpdApdGpdApdGp-3'
61 19035.35 g/mole 602700.00 L/(mole·cm) 63.93% 1.66 31.58

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Torabi, S., Wu, P., McGhee, C., Chen, L., Hwang, K., Zheng, N., Cheng, J., & Lu, Y. (2015) In Vitro Selection of a Sodium-Specific DNAzyme and its Application in Intracellular Sensing. PNAS 112, (19):5903-5908

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