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Apta-Index™: AP-1 cJun/cJun Aptamer-19 (ID# 586)

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AP-1 cJun/cJun Aptamer-19 (ID# 586)

AP-1 cJun/cJun Aptamer-19
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Activator Protein-1 Family cJun/cJun Homodimer Protein 0.5 nM (reported value) binding buffer (20 mM Tris (pH 7.9), 0.1 mM EDTA, 10% glycerol, 1 mM DTT, 150 mM KCl, 5 mM MgCl2, 0.04% NP-40) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
dGpdGpdGpdApdGpdApdTpdCpdApdCpdTpdTpdApdCpdGpdGpdCpdApdCpdCpdGpdTpdApdTpdApdGpdTpdCpdGpdTpdApdCpdApdTpdGpdApdApdCpdGpdApdGpdTpdGpdTpdGpdApdGpdTpdGpdTpdTpdApdApdGpdCpdCpdTpdTpdTpdGpdGpdCpdGpdApdCpdApdGpdGpdGpdCpdTpdCpdGpdGpdApdApdCpdCp
78 24206.74 g/mole 762100.00 L/(mole·cm) 53.85% 1.31 31.76

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Walters RD, McSwiggen DT, Goodrich JA, Kugel JF (2014) Selection and Characterization of a DNA Aptamer That Can Discriminate between cJun/cJun and cJun/cFos. PLoS ONE 9(6): e101015. doi:10.1371/journal.pone.0101015

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