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Apta-Index™: Aptamer TY04 (ID# 584)

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Aptamer TY04 (ID# 584)

Aptamer TY04
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Multiple myeloma cells (MM.1S) Cells 3.89 µM (reported value) yeast tRNA (0.1mg/ml; Sigma) and BSA (1 mg/ml; Sigma) into the wash buffer N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
dApdTpdCpdGpdTpdCpdTpdGpdCpdTpdCpdCpdGpdTpdCpdCpdApdApdTpdApdTpdApdTpdCpdApdApdApdGpdGpdCpdGpdApdApdTpdTpdTpdTpdGpdTpdCpdApdApdGpdGpdTpdGpdTpdTpdApdApdApdCpdGpdApdTpdApdGpdTpdCpdCpdCpdTpdApdCpdCpdTpdTpdTpdGpdGpdTpdGpdTpdGpdApdGpdGpdTpdCpdGpdTpdGpdCp
83 25587.67 g/mole 794400.00 L/(mole·cm) 45.78% 1.26 32.21

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Dai, H. et al. "Aptamer TY04 inhibits the growth of multiple myeloma cells via cell cycle arrest." Tumor Biology 2014: 1-8.

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