Aptamer Details

TGF-??1 (T18_1_3) (ID# 58)

Aptamer Chemistry: DNA Target: Transforming Growth Factor-??1 (TGF-??1) Antigen/Target Category: Protein Affinity (Kd): 94 nM (reported value) Binding Conditions/Buffer: PBS with 1 MgCl₂. Binding Temp: RT°C Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Comments:

Sequence (): 5'dCpdGpdCpdTpdCpdGpdGpdCpdTpdTpdCpdApdCpdGpdApdGpdApdTpdTpdCpdGpdTpdGpdTpdCsdGpdTpdTpdGpdTpdGpdTpdCsdCsdTpdGpdTpdAsdCsdCsdCsdGpdCsdCsdTpdTpdGpdAsdCsdCsdAsdGpdTpdCsdAsdCsdTpdCsdTpdAsdGpdAsdGpdCsdAsdTpdCsdCsdGpdGpdAsdCsdTpdGp3' Length: 74 Molecular Weight: 23064.62 g/mole Extinction Coefficient: 673000 L/(mole·cm) GC Content: 58.11% nmoles/OD₂₆₀: 1.49 μg/OD₂₆₀: 34.27

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Kang, Jonghoon, et al. "Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-??1 protein." Bioorganic & Medicinal Chemistry Letters, 18 (2008): 1835-1839.

Have your aptamer oligo synthesized ORDER NOW

Aptamer Details

TGF-??1 (T18_1_3) (ID# 58)

Kang, Jonghoon, et al. "Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-??1 protein." Bioorganic & Medicinal Chemistry Letters, 18 (2008): 1835-1839.

Related Aptamer Targets

Community Feedback