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Apta-Index™: S132B-C22 (ID# 565)

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S132B-C22 (ID# 565)

S132B-C22
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Botulinum Neuroxin Type A (BoNT/A) Protein 0.8 nM (reported value) PBS, pH 7.4, 300mM NaCl, 3mM MgCl2, 5mM DTT, 1mg/ml BSA, 0.2% Tween, 1mg/ml heparin N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
rGprAprCprAprGprCprGpUrGprCprCpUrAprGprAprAprGpUrCprCprAprAprGprCpUUrAprAprApUrAprAprCprCprAprCprGprCpUrCprGprAprCprAprAprGprCp
40 12930.02 g/mole 395100.00 L/(mole·cm) 60.00% 2.53 32.73

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Tzuu-Wang Chang, Michael Blank, Pavithra Janardhanan, Bal Ram Singh, Charlene Mello, Michael Blind, Shuowei Cai, "In vitro selection of RNA aptamers that inhibit the activity of type A botulinum neurotoxin" Biochemical and Biophysical Research Communications 396 (2010) 854–860.

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