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Apta-Index™: Clone 488 (ID# 560)

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Clone 488 (ID# 560)

Clone 488
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA SelB Protein nM (reported value) 50 mM potassium phosphate, pH 7.0, 5 mM Mg(OAc)2, 0.1 mM EDTA, 1 mM DTT, 0.5 mM GTP,0.02% Tween 20, 400 U/mL RNAsin N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
dGpdCpdGpdCpdTpdApdApdGpdTpdCpdCpdTpdCpdGpdCpdTpdCpdApdGpdCpdCpdCpdApUdApdApdGpUUdGpUdCpdCpdCpdApdApdGpUdCpUUdGpdGpdGpdCpdGpdCpdApdApdApUdApdCpdApUdCpdCpdCpdApdCpdGpdCpdGpdCpdGpdApdCpdTpdCpdGpdGpdApdTpdCpdCpdGp
67 20508.24 g/mole 621000.00 L/(mole·cm) 67.16% 1.61 33.02

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Klug, S. J. et al. "In vitro selection of RNA aptamers that bind special elongation factor SelB, a protein with multiple RNA-binding sites, reveals one major interaction domain at the carboxyl terminus." RNA, 1995 5: 1180 - 1190.

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