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Apta-Index™: GL21.T (ID# 552)

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GL21.T (ID# 552)

GL21.T
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Axl tyrosine kinase receptor Protein 12 nM (reported value) Dulbecco's Modified Eagle's Medium (DMEM), 10% FBS, 2mM L-glutamine 85C for 5 minutes, snap cooled on ice for 2 minutes, and then warmed up to 37C. Note that the sequence is 2'-fluoropyrimidine, 2'-ribopurine (see reference paper).
5'-rApfUprGprApfUpfCprAprApfUpfCprGpfCpfCpfUpfCprAprApfUpfUpfCprGprApfCprAprGprGprAprGprGpfCpfUpfCprApfCp-3'
34 10875.53 g/mole 335000.00 L/(mole·cm) 50.00% 2.99 32.46

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Laura Cerchia, Carla L Esposito, Simona Camorani, Anna Rienzo, Loredana Stasio, Luigi Insabato, Andrea Affuso and Vittorio de Franciscis,"Targeting Axl With an High-affinity Inhibitory Aptamer". Molecular Therapy vol.20 no.12, 2291-2303, Dec2012.

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