* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA HA protein (gHA1) Protein nM (reported value)20 mM sodium phosphate, pH 7.5, 500 mM NaCl and 20 mM imidazoleN/A
If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Kwon, H. et al. "An RNA Aptamer That Specifically Binds to the Glycosylated Hemagglutinin of Avian Influenza Virus and Suppresses Viral Infection in Cells." PLOS One 2014, 9 1-9.
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* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA
HA protein (gHA1)
Protein
nM (reported value)
20 mM sodium phosphate, pH 7.5, 500 mM NaCl and 20 mM imidazole
N/A
If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
