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Apta-Index™: Periostin Aptamer (PNDA-3) (ID# 530)

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Periostin Aptamer (PNDA-3) (ID# 530)

Periostin Aptamer (PNDA-3)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Periostin Protein 1.07 nM (reported value) 40 mM/1 HEPES, 102 mM/1 NaCl, 5 mM/1mol/1g Cl2,5 mM KCl N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. 5' benzylaminocarbonyl-d U modification
dApdCpdGpdApdGpdTpdTpdGpdTpdCpdGpdCpdApdTpdGpdTpdGpdCpdGpdGpdTpdTpdCpdApdGpdTpdCpdTpdGpdGpdTpdCpdCpdTpdTpdCpdApdGpdCpdApdCpdCpdGpdTpdAp dCpdApdApdCpdApdAp
51 15666.20 g/mole 483400.00 L/(mole·cm) 52.94% 2.07 32.41

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Lee, Y., Kim, I., Park, S., Kim, Y., Wu, S., Lee, J., Noh, D., Kim, K., Ryu, S. and Suh, P. "Periostin-binding DNA aptamer inhibits breast cancer growth and metastasis." The American Society of Gene & Cell Therapy 21.5 (2013): 1004-13.

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