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Apta-Index™: NS-1 Aptamer (ID# 516)

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NS-1 Aptamer (ID# 516)

NS-1 Aptamer
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Influenza A virus (IAV) non-stuctural protein (NS1) Protein 18.91 nM (reported value) 50 mM Tris/Cl (pH 8.0), 150 mM NaCl, 1.5 mM MgCl2, 2 mM DTT and 1% (w/v) BSA N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
dGpdCpdApdApdTpdGpdGpdTpdApdCpdGpdGpdTpdApdCpdTpdTpdCpdCpdGpdCpdGpdGpdTpdCpdCpdGpdGpdGpdGpdTpdGpdGpdGpdTpdGpdGpdGpdTpdGpdGpdTpdGpdGpdGpdGpdGpdGpdTpdGpdCpdGpdGpdGpdGpdGpdGpdGpdCpdGpdGpdCpdCpdGpdCpdApdApdApdApdGpdTpdGpdCpdApdCpdGpdCpdTpdApdCpdTpdTpdTpdGpdCpdTpdApdAp
88 27570.81 g/mole 834900.00 L/(mole·cm) 67.05% 1.20 33.02

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Woo, H., Kim, K., Lee, J., Shim, H., Cho, S., Lee, W., Ko, H., Keum, Y., Kim, S., Pathinayake, P., Kim, C., and Jeong, Y. "Single-stranded DNA aptamer that specifically binds to the influenza virus NS1 protein suppresses interferon antagonism." Antiviral Research 100.2(2013): 337-345.

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