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Apta-Index™: VEGF (3R02 bivalent) (ID# 493)

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VEGF (3R02 bivalent) (ID# 493)

VEGF (3R02 bivalent)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Vascular Endothelial Growth Factor (VEGF) Protein 30 pM (reported value) Binding buffer: 10 mM Tris-HCl, 100 mM NaCl, and 5 mM KCl (pH 7.4) Heat to 95°C for 5 minutes in binding buffer, then gradually cool. Bivalent. Each monomer is expected to form an anti-parallel G-quadruplex.
5'-dTpdGpdTpdGpdGpdGpdGpdGpdTpdGpdGpdApdCpdTpdGpdGpdGpdTpdGpdGpdGpdTpdApdCpdCpdTpdTpdTpdTpdTpdTpdTpdTpdTpdTpdTpdGpdTpdGpdGpdGpdGpdGpdTpdGpdGpdApdCpdTpdGpdGpdGpdTpdGpdGpdGpdTpdApdCpdCp-3'
60 18836.24 g/mole 560300.00 L/(mole·cm) 56.67% 1.78 33.62

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Nonaka, Y. "Affinity Improvement of a VEGF Aptamer by in Silico Maturation for a Sensitive VEGF-Detection System." Anal. Chem., 85 (2013): 1132-1137.

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