Aptagen, LLC
DNA
Vascular Endothelial Growth Factor (VEGF)
Protein
30 pM (reported value)
Binding buffer: 10 mM Tris-HCl, 100 mM NaCl, and 5 mM KCl (pH 7.4)
20°C
Heat to 95°C for 5 minutes in binding buffer, then gradually cool.
Bivalent. Each monomer is expected to form an anti-parallel G-quadruplex.
VEGF (3R02 bivalent) (ID# 493)
5'dTpdGpdTpdGpdGpdGpdGpdGpdTpdGpdGpdApdCpdTpdGpdGpdGpdTpdGpdGpdGpdTpdApdCpdCpdTpdTpdTpdTpdTpdTpdTpdTpdTpdTpdTpdGpdTpdGpdGpdGpdGpdGpdTpdGpdGpdApdCpdTpdGpdGpdGpdTpdGpdGpdGpdTpdApdCpdCp3'
60
18836.24 g/mole
560300 L/(mole·cm)
56.67%
1.78
33.62
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Nonaka, Y. "Affinity Improvement of a VEGF Aptamer by in Silico Maturation for a Sensitive VEGF-Detection System." Anal. Chem., 85 (2013): 1132-1137.
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