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Apta-Index™: Anterior Gradient Homolog 2 (C14B0) (ID# 478)

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Anterior Gradient Homolog 2 (C14B0) (ID# 478)

Anterior Gradient Homolog 2 (C14B0)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Anterior Gradient Homolog 2 (AGR2) Protein 8.5 nM (reported value) Binding Buffer: PBS with 137 mM NACl, 2.7 mM KCl, 10 mM NaHPO4, and 2.0 mM KH2PO4 Denatured at 95° C for 5 minutes, subsequently cooled on ice for 10 minutes. Then incubated at RT for 10 minutes. Aptamer is expected to form a G-quartet.
5'-dTpdCpdTpdCpdGpdGpdApdCpdGpdCpdGpdTpdGpdTpdGpdGpdTpdCpdGpdGpdCpdGpdGpdGpdTpdGpdGpdGpdApdGpdTpdTpdGpdTpdGpdGpdGpdGpdGpdGpdGpdGpdGpdTpdGpdGpdGpdApdGpdGpdGpdTpdTpdCpdTpdTpdTpdGpdTpdTpdTpdGpdApdTpdCpdTpdTpdTpdCpdTpdCpdGpdCpdTpdGpdCpdCpdTpdGpdGpdCpdCpdCpdTpdApdGpdApdGpdTpdGpdTpdCpdGpdCpdTpdGpdCpdCpdTpdGpdGpdCpdApdGpdApdGpdTpdGp-3'
108 33748.78 g/mole 995300.00 L/(mole·cm) 63.89% 1.00 33.91

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Wu et al. "Identification, Characterization and Amplification of a G-Quadruplex Structured DNA Aptamer Against Cancer Biomarker Protein Anterior Gradient Homolog 2." PLOS, 9 (2012):e46393.

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