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Apta-Index™: Interleukin-6 receptor (AIR-3A) (ID# 474)

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Interleukin-6 receptor (AIR-3A) (ID# 474)

Interleukin-6 receptor (AIR-3A)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Cells presenting IL-6R Cells 8.5 nM (reported value) Selection Buffer (used for Filter Retention Assay): 137 mM NaCl, 2.7 mM KCl, 6.5 mM Na2HPO4, and 3 mM MgCl2 at PH 7.5. None Listed Forms a G-quartet structure.
This aptamer is a truncated version of AIR-3 and binds to IL-6r presenting cells. It is then internalized and was used by Meyer et al. do deliver fluorescently labeled strptavidin.
5'-rGprGprGprGprAprGprGprCprUprGprUprGprGprUprGprAprGprGprGp-3'
19 6307.88 g/mole 193400.00 L/(mole·cm) 73.68% 5.17 32.62

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Meyer C, U Hahn, et al. (2012) Interleukin-6 Receptor specific RNA aptamers for cargo delivery into target cells. RNA Biol

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