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Apta-Index™: Lysergamine (M3.2) (ID# 470)

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Lysergamine (M3.2) (ID# 470)

Lysergamine (M3.2)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Lysergamine, metergoline, and other small ergot alkaloids Protein 44 nM (reported value) Binding Buffer: 100 mM NaCl, 20 mM Tris-HCl (pH 7.6), 5 mM KCl, 2 mM MgCl2 ·6 H2O, 1 mM CaCl2·2 H2O. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. The aptamer contains two cytosine-repeat binding sites.
5'-dApdGpdCp dApdGpdCp dApdCpdAp dGpdApdGp dGpdTpdCp dApdGpdAp dTpdGpdGp dCpdGpdTp dCpdApdGp dCpdCpdCp dCpdGpdAp dTpdCpdGp dCpdCpdAp dTpdCpdCp dApdGpdGp dGpdApdCp dTpdCpdCp dCpdCpdCp dCpdTpdAp dCpdTpdGp dCpdCp dTpdApdTp dGpdCpdGp dTpdGpdCp dTpdApdCp dCpdGpdTp dGpdApdAp-3'
80 24516.84 g/mole 747200.00 L/(mole·cm) 62.50% 1.34 32.81

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

ER Martin et al. (2012) Aptamer-based molecular recognition of lysergamine, metergoline and small ergot alkaloids. Int. J. Mol. Sci. 13: 17138-17159.

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