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Apta-Index™: Influenza B Hemagglutinin (A20) (ID# 443)

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Influenza B Hemagglutinin (A20) (ID# 443)

Influenza B Hemagglutinin (A20)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Influenza B Hemagglutinin (HA) Protein 720 pM (reported value) Binding Buffer: 50 mM Tris-HCl, pH 7.5, 25 mM NaCl, 5 mM MgCl2. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. This aptamer inhibited HA-mediated membrane fusion in human red blood cell ghost membranes.
5'-rGprGprGprAprGprCprUprCprAprGprCprCprUprUprCprAprCprUprGprCprAprCprUprCprCprGprGprCprUprGprGprUprGprGprAprCprGprCprGprGprUprAprCprGprAprGprCprAprAprUprUprUprGprUprAprCprCprGprGprAprUprGprGprAprUprGprUprUprCprGprGprGprCprAprGprCprGprGprUprGprUprGprGprCprAprGprGprGprAprUprGprAprGprCprGprGprCprAprCprCprAprCprGprGprUprCprGprGprAprUprCprCprAprCp-3'
114 36951.24 g/mole 1096100.00 L/(mole·cm) 64.04% 0.91 33.71

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

S. Gopinath et al. An efficient RNA aptamer against human influenza B virus hemagglutinin. J. Biochem. 139(2006): 837-846.

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