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Apta-Index™: L-Selectin (LD201t1) (ID# 407)

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L-Selectin (LD201t1) (ID# 407)

L-Selectin (LD201t1)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA L-Selectin binding to sialyl Lewis X Protein 3 nM (reported value) Binding Buffer (20 mM Hepes, 111 mM NaCl, 1 mM CaCl2, 1 mM MgCl2, 5 mM KCl, 8.9 mM NaOH final pH 8) and 1% globulin-free BSA. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dTpdApdGpdCpdCpdApdApdGpdGpdTpdApdApdCpdCpdApdGpdTpdApdCpdApdApdGpdGpdTpdGpdCpdTpdApdApdApdCpdGpdTpdApdApdTpdGpdGpdCpdTpdTpdCpdGpdGpdCpdTpdTpdApdCp-3'
49 15113.89 g/mole 481400.00 L/(mole·cm) 46.94% 2.08 31.40

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Hicke, Brain, et al. "DNA Aptamers Block L-Selectin Function In Vivo Inhibition of Human Lymphocyte Traf?cking in SCID Mic." Journal of Clinical Investigation, 98 (1996): 2688-2692

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