Aptagen, LLC
DNA
Dopamine
Small Organic
0.7 µM (reported value)
Buffer: 50 mM Tris-HCl (pH 7.4), 5 mM MgCl2, and 0.5 M
N/A°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Aptamer has a similar affinity to related molecules dopamine and norepinephrine but much lower affinity for tyramine
This aptamer is a homolog of dopamine aptamer dopa1.30/c.30.
Dopamine (DNA version of dopa1.30/c.30) (ID# 403)
5'dGpdTpdCp dTpdCpdTp dGpdTpdGp dTpdGpdCp dGpdCpdCp dApdGpdAp dGpdApdAp dCpdApdCp dTpdGpdGp dGpdGpdCp dApdGpdAp dTpdApdTp dGpdGpdGp dCpdCpdAp dGpdCpdAp dCpdApdGp dApdApdTp dGp dApdGpdGp dCpdCpdCp3'
65
17982.68 g/mole
561000 L/(mole·cm)
60.34%
1.78
32.05
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
R Walsh and M DeRosa. Retention of function in the DNA homolog of the RNA dopamine aptamer. Biochem. Biophys. Res. Commun. 388(2009): 732-735.
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