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Apta-Index™: Ethanolamine (14.3) (ID# 39)

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Ethanolamine (14.3) (ID# 39)

Ethanolamine (14.3)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Ethanolamine Small Organic 6 nM (reported value) Binding Buffer (100 mM NaCl, 20 mM Tris/HCl (pH 7.6), 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% Tween 20). N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dApdTpdApdCpdCpdApdGpdCpdTpdTpdApdTpdTpdCpdApdApdTpdTpdTpdGpdApdGpdGpdCpdGpdGpdGpdTpdGpdGpdGpdTpdGpdGpdGpdTpdTpdGpdApdApdTpdApdTpdGpdCpdTpdGpdApdTpdTpdApdCpdCpdCpdCpdApdTpdCpdGpdGpdApdGpdApdApdCpdGpdTpdTpdApdApdGpdGpdCpdGpdCpdTpdTpdCpdApdGpdApdTpdApdGpdTpdApdApdGpdTpdGpdCpdApdApdTpdCpdTp-3'
96 29786.42 g/mole 940500.00 L/(mole·cm) 45.83% 1.06 31.67

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Mann, Doerthe, et al. "In vitro selection of DNA aptamers binding ethanolamine." Biochemical and Biophysical Research Communication, 338 (2005): 1928-1934. Tradmarked in patent, "New DNA aptamers specific for compunds that contain the ethylamino group, useful for diagnosis, prevention and treatment of ethanolaminosis, schizophrenia and neurodegeneration (Original document: DE 102005052275 (B4))"

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