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Apta-Index™: Tumor-derived endothelial cells (PepMW3) (ID# 383)

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Tumor-derived endothelial cells (PepMW3) (ID# 383)

Tumor-derived endothelial cells (PepMW3)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peptide Tumor-derived endothelial cells (TDECs) Cells N/A nM (reported value) IMC Medium: 1X M9 Salts (40 mM Na2HPO4, 20 mM KH2PO4, 8.5 mM NaCl, 20 mM NH4Cl, pH 7.4), 0.2% casamino acids, 0.5% glucose, 1 mM MgCl2.
Incubation/Wash solution: IMC medium containing 10% fetal calf serum (FCS) and 1% a-methyl mannoside.
N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-CysGlyGlyArgArgLeuGlyGlyCys-3'
9 960.21 g/mole

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

C K Brown et al. A novel approach for the identificaiton of unique tumor vasculature binding peptides using an E. coli peptide display library. Ann Surg Oncol. 7(2000): 743-749.

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