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Apta-Index™: CD59 (sp22) (ID# 381)

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CD59 (sp22) (ID# 381)

CD59 (sp22)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peptide CD59 Protein N/A nM (reported value) Washed with cold PBS and glycine buffer added. Chilled on ice for 15 minutes. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Inhibits CD59 expression; Concomitantly, sp22 increases complement-mediated lysis and apoptosis signals.
5'-AlaCysHisTrpProTrpCysHisGlyTrpHisSerAlaCysAspLeuProMetHisProMetCys-3'
22 2922.43 g/mole

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Li et al. "Identification of a novel short peptide seal specific to CD59 and its effect on HeLa cell growth and apoptosis." Cell Oncol. 35:355-365.

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