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Apta-Index™: V7t1 targeting VEGF-165 (ID# 368)

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V7t1 targeting VEGF-165 (ID# 368)

V7t1 targeting VEGF-165
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA VEGF-165 Protein 1.4 nM (reported value) 10% (v/v) human serum in TBSTE (TBSE containing 0.05% (v/v) of Tween-20). N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
25 7900.16 g/mole 248000.00 L/(mole·cm) 72.00% 4.03 31.86

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Nonaka,Y., Sode, K., and Ikebukuro, K.(2010) "Screening and Improvement of an Anti-VEGF DNA Aptamer." Molecules, 15, 215-225.
Stejskalová, Anna & Oliva, Nuria & J England, Frances & Almquist, Benjamin. (2019). Biologically Inspired, Cell-Selective Release of Aptamer-Trapped Growth Factors by Traction Forces. Advanced Materials. 1806380. 10.1002/adma.201806380.

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