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Apta-Index™: HIV-1 Tat protein (ID# 364)

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HIV-1 Tat protein (ID# 364)

HIV-1 Tat protein
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA HIV-1 Tat protein Protein 120 pM (reported value) Binding Buffer: 50 mM Tris-HCl (pH 7.8) and 50 mM KCl N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'- rAprCprGprAprAprGprCprUprUprGp rAprUprCprCprCprGprUprUprUprGp rCprCprGprGprUprCprGprAprUprCp rGprCprUprUprCprGprAp-3'
37 11784.08 g/mole 352600.00 L/(mole·cm) 56.76% 2.84 33.42

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

R Yamamoto et al. A novel RNA motif that binds efficiently and specifically to the Tat protein of HIV and inhibits the trans-activation by Tat of transcription in vitro and in vivo. Genes to Cells 5(2000):371-388

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