* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA HIV-1 Tat protein Protein 120 pM (reported value)Binding Buffer: 50 mM Tris-HCl (pH 7.8) and 50 mM KClN/A
If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
R Yamamoto et al. A novel RNA motif that binds efficiently and specifically to the Tat protein of HIV and inhibits the trans-activation by Tat of transcription in vitro and in vivo. Genes to Cells 5(2000):371-388
Have your aptamer oligo synthesized by one of our AFFILIATES
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA
HIV-1 Tat protein
Protein
120 pM (reported value)
Binding Buffer: 50 mM Tris-HCl (pH 7.8) and 50 mM KCl
N/A
If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
