Aptagen, LLC
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA
mEGFR and hEGFR
Protein
29 nM (reported value)
1X DPBS, 5mM MgCl2, pH 7.1-7.5
25°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Kd value listed is for mEGFR. The Kd value of this aptamer for hEGFR is 3.0 nM. See also Anti-EGFR E07.
Anti-EGFR (E03) (ID# 357)
5' rGprGpfCprGpfCpfUpfCpfCprGprAp fCpfCpfUpfUprAprGpfUpfCpfUpfCp fUprGpfUprGpfCpfUprAprGpfUprAp fUprApfUpfCprGpfCprApfCprGprGp rApfUpfUpfUprAprApfUpfCprGpfCpfCprGpfUprAprGprAprAprAprAprGp fCprApfUprGpfUpfCprAprAprAprGp fCpfCprGprGprAprApfCpfCprGpfUp rGpfUprAprGpfCprApfCprAprGpfCp rAprGprAp3'
96
29988.85 g/mole
921300 L/(mole·cm)
51.61%
1.09
32.55
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
N. Li et al. "Inhibition of Cell Proliferation by an Anti-EGFR Aptamer." PLoS One 6(2011): e20299.
Have your aptamer oligo synthesized ORDER NOW
We are always looking for ways to improve. Please tell us what you think.