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Apta-Index™: C-Reactive Protein (CRP) (ID# 353)

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C-Reactive Protein (CRP) (ID# 353)

C-Reactive Protein (CRP)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA C-Reactive Protein (CRP) Protein 3.51 nM (reported value) DNA and CRP-conjugated magnetic beads mixed and incubated utilizing a membrane-type micropump/micromixer (for about 5min). Dissociation constant determined using a SPR technique. SPR Buffer: 10 mM Tris buffer with 50 mM NaCl and 2 mM CaCl2. Not mentioned in the reference.
5'-dGpdGpdCp dApdGpdGp dApdApdGp dApdCpdAp dApdAp dCpdApdCp dGpdApdTp dGpdGpdGp dGpdGpdGp dGpdTpdAp dTpdGpdAp dTpdTpdTp dGpdApdTp dGpdTpdGp dGpdTpdTp dGpdTpdTp dGpdCpdAp dTpdGpdAp dTpdCpdGp dTpdGpdGp dTpdCpdTp dGpdTpdGp dGpdTpdGp dCpdTpdGp dTp-3'
72 22571.71 g/mole 704600.00 L/(mole·cm) 51.39% 1.42 32.03

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

C-J Huang et al. "Integrated microfluidic system for rapid screening of CRP aptamers utilizing systematic evolution of ligands by exponential enrichment (SELEX)." Biosens. Bioelectron. 25(2010):1761-1766.

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