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Apta-Index™: Human Hepatocellular carcinoma (TLS11a) (ID# 286)

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Human Hepatocellular carcinoma (TLS11a) (ID# 286)

Human Hepatocellular carcinoma (TLS11a)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Human Hepatocellular carcinoma cell line (LH86) Cells 7.16 nM (reported value) Binding buffer (PBS containing 5 mM MgCl2, 4.5 mg/mL glucose, 0.1 mg/mL yeast tRNA, 1 mg/mL BSA) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dApdCpdApdGpdCpdApdTpdCpdCpdCpdCpdApdTpdGpdTpdGpdApdApdCpdApdApdTpdCpdGpdCpdApdTpdTpdGpdTpdGpdApdTpdTpdGpdTpdTpdApdCpdGpdGpdTpdTpdTpdCpdCpdGpdCpdCpdTpdCpdApdTpdGpdGpdApdCpdGpdTpdGpdCpdTpdGp-3'
63 19339.58 g/mole 589200.00 L/(mole·cm) 50.79% 1.70 32.82

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Meng, L. (2012). Targeted delivery of chemotherapy agents using liver cancer-specific aptamer. PloS One, 7(4), doi: 10.1371

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