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Apta-Index™: Non-small Cell Lung Cancer (S6) (ID# 271)

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Non-small Cell Lung Cancer (S6) (ID# 271)

Non-small Cell Lung Cancer (S6)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA Non-small Cell Lung Cancer Cells 28.2 nM (reported value) Wash Buffer (5 mmol MgCl2 and 4.5 g glucose into 1 L of Dulbecco’s PBS without calcium and magnesium) The binding buffer was prepared by adding 1 mg/mL bovine serum albumin (BSA) and 0.1 mg/mL yeast tRNA to washing buffer N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dApdCpdGpdCpdTpdCpdGpdGpdApdTpdGpdCpdCpdApdCpdTpdApdCpdApdGpdGpdTpdGpdGpdCpdCpdApdGpdTpdCpdApdCpdTpdCpdApdApdTpdTpdGpdGpdGpdTpdGpdTpdApdGpdGpdGpdGpdTpdGpdGpdGpdGpdApdTpdTpdGpdTpdGpdGpdGpdTpdTpdGpdCpdTpdCpdApdTpdGpdGpdApdCpdGpdTpdGpdCpdTpdGpdGpdTpdGpdApdCp-3'
85 26491.17 g/mole 809200.00 L/(mole·cm) 58.82% 1.24 32.74

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Zhao et al. "Recognition of subtype non-small cell lung cancer by DNA aptamers selected from living cells." Analyst 134(2009):1808-1814.

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