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Apta-Index™: ADP (ID# 262)

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ADP (ID# 262)

ADP
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA ADP Small Organic 1-5 µM (reported value) Selection Buffer ((50 mM HEPES [pH 7.4], 25 mM MgCl2, 150 mM NaCl) containing 10 g/ml tRNA) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Contains a hammerhead ribozyme motif.
5'-rGprGprGprCprGprAprCprCprCprUprGprAprUprGprAprGprCprAprCprAprCprGprAprGprGprGprGprGprAprAprAprCprCprCprCprGprGprAprCprAprAprUprCprAprGprAprCprAprCprGprGprUprGprUprUprCprGprAprAprAprCprGprGprUprGprAprAprAprGprCprCprGprUprAprGprGprUprUprGprCprCprCprUprUprUp-3'
85 27540.71 g/mole 837700.00 L/(mole·cm) 58.82% 1.19 32.88

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Srinivasan et al. "ADP-Specific Sensors Enable Universal Assay of Protein Kinase Activity." Chemistry & Biology, 11(2004): 499-508.

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