Aptagen, LLC
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peptide
Islets of Langerhans
Tissue
N/A nM (reported value)
In vivo in mice with body temperature maintained at 37 °C.
N/A°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Cyclic through N- and C-terminal disulfide bond.
This peptide aptamer is similar to a region in the N-terminus of the ephrin-A2 ligand and binds to the EphA2 receptor.
Islets of Langerhans (ID# 250)
This peptide aptamer is similar to a region in the N-terminus of the ephrin-A2 ligand and binds to the EphA2 receptor.
NH2CysValSerAsnProArgTrpLysCysCOOCOOH
9
1174.47 g/mole
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Yao et al. "Targeting Pancreatic Islets with Phage Display Assisted by Laser Pressure Catapult Microdissection." American Journal of Pathology, 166(2005): 625-636.
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