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Apta-Index™: Histone H3R8Me2sym (Clone 1) (ID# 224)

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Histone H3R8Me2sym (Clone 1) (ID# 224)

Histone H3R8Me2sym (Clone 1)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Histone H3R8Me2sym Peptide 12 nM (reported value) N/A N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Truncated versions of the aptamer were investigated, but exhibited lower affinities for the target.
5'-rGprGprGprAprCprGprCprGprUprGprGprUprAprCprCprGprAprUprGprGprGprUprCprAprGprCprAprUprGprUprAprGprCprCprAprGprGprCprAprGprGprGprCprCprGprUprGprUprGprAprGprCprUprUprGprUprGprCprUprGprAprUprGprUprGprAprGprCprUprUprCprCprGprCprGprGprGprGprAprUprCp-3'
81 26323.83 g/mole 784200.00 L/(mole·cm) 64.20% 1.28 33.57

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Hyun et al. "An RNA Aptamer That Selectively Recognizes Symmetric Dimethylation of Arginine 8 in the Histone H3 N-Terminal Peptide." Nucleic Acid Therapeutics, 21 (2011): 157-163.

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