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Apta-Index™: Bevacizumab-Responsive Peptide (BRP) (ID# 220)

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Bevacizumab-Responsive Peptide (BRP) (ID# 220)

Bevacizumab-Responsive Peptide (BRP)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peptide Bevacizumab-treated Tumor Tissue N/A nM (reported value) Intracardiac injection of phage libraries. Amplified phages were partially purified by polyethyleneglycol(PEG) precipitation and resuspended in tris-buffered saline (TBS). N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
NH2-LeuLeuAlaAspThrThrHisHisArgProTrpThr-COOH
12 1583.81 g/mole

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Cao et al. "Phage display peptide probes for imaging early response to bevacizumab treatment." Amino Acids, 41(2011): 1103-1112.

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