* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA RIG-I Protein 37.2 nM (reported value)1X PBS with 1 mM MgCl2N/A
If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.2'-F-RNA (C's and U's Only)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Hwang et al. "5'-Triphosphate-RNA-independent activation of RIG-1 via RNA aptamer with enhanced antiviral activity." Nucleic Acids Research 40(2011): 2724 - 2733
Have your aptamer oligo synthesized by one of our AFFILIATES
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA
RIG-I
Protein
37.2 nM (reported value)
1X PBS with 1 mM MgCl2
N/A
If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
2'-F-RNA (C's and U's Only)
