Aptagen, LLC
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA
RIG-I
Protein
37.2 nM (reported value)
1X PBS with 1 mM MgCl2
4°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
2'-F-RNA (C's and U's Only)
RIG-I (CL9) (ID# 216)
5'rGprGprGprAprGprAprGpfCprGprGprAprAprGpfCprGpfUprGpfCpfUprGprGprGpfCpfCprApfCpfCprApfUpfCpfCprGpfUprAprApfCpfUprAprGpfCpfUprAprApfUprApfCpfUpfUprGpfUpfUprApfUpfCpfUpfUpfUpfUpfUprApfUpfUpfUpfUpfCprApfUprAprApfCpfCpfCprAprGprAprGprGpfUpfCprGprApfUprGprGprApfUpfCpfCpfCpfCpfCpfCp3'
92
29522.39 g/mole
900600 L/(mole·cm)
50.00%
1.11
32.78
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Hwang et al. "5'-Triphosphate-RNA-independent activation of RIG-1 via RNA aptamer with enhanced antiviral activity." Nucleic Acids Research 40(2011): 2724 - 2733
Have your aptamer oligo synthesized ORDER NOW
We are always looking for ways to improve. Please tell us what you think.