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Apta-Index™: RIG-I (CL9) (ID# 216)

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RIG-I (CL9) (ID# 216)

RIG-I (CL9)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA RIG-I Protein 37.2 nM (reported value) 1X PBS with 1 mM MgCl2 N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. 2'-F-RNA (C's and U's Only)
5'-rGprGprGprAprGprAprGpfCprGprGprAprAprGpfCprGpfUprGpfCpfUprGprGprGpfCpfCprApfCpfCprApfUpfCpfCprGpfUprAprApfCpfUprAprGpfCpfUprAprApfUprApfCpfUpfUprGpfUpfUprApfUpfCpfUpfUpfUpfUpfUprApfUpfUpfUpfUpfCprApfUprAprApfCpfCpfCprAprGprAprGprGpfUpfCprGprApfUprGprGprApfUpfCpfCpfCpfCpfCpfCp-3'
92 29522.39 g/mole 900600.00 L/(mole·cm) 50.00% 1.11 32.78

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Hwang et al. "5'-Triphosphate-RNA-independent activation of RIG-1 via RNA aptamer with enhanced antiviral activity." Nucleic Acids Research 40(2011): 2724 - 2733

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