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Apta-Index™: TLR3-ECD (Family-1) (ID# 211)

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TLR3-ECD (Family-1) (ID# 211)

TLR3-ECD (Family-1)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA Toll-like receptor 3 Ectodomain Protein 2.1 nM (reported value) Binding buffer: 2 mM HEPES-NaOH (pH 7.6), 3 mM MgCl2, and 100 mM NaCl N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprUprAprGprAprUprAprCprGprAprUprGprGprAprUprAprCprCprCprCprCprUprGprUprGprGprCprCprCprGprUprCprAprAprCprAprCprAprGprGprGprGprAprAprGprUprGprGprCprAprUprGprAprCprGprCprGprCprAprGprCprCprAp-3'
64 20703.58 g/mole 628900.00 L/(mole·cm) 60.94% 1.59 32.92

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Watanabe et al. "Isolation of RNA aptamers against human Toll-like receptor 3 ectodomain." Nucleic Acids Symposium Series No. 50 (2006): 251-252.

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