b>276(2001): 16464-16468.">
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Apta-Index™: YPEN-1 Endothelial Cells (III.1) (ID# 210)

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YPEN-1 Endothelial Cells (III.1) (ID# 210)

YPEN-1 Endothelial Cells (III.1)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
DNA YPEN-1 Endothelial Cells Cells N/A nM (reported value) Selection buffer: 50 mM Tris-HCl (pH 7.4), 5 mM KCl, 100 mM NaCl, 1 mM MgCl2, and 0.1% NaN3 with 1 ug/uL yeast tRNA. N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dApdTpdApdCpdCpdApdGpdCpdTpdTpdApdTpdTpdCpdApdApdTpdTpdApdGpdGpdCpdGpdGpdTpdGpdCpdApdTpdTpdGpdTpdGpdGpdTpdTpdGpdGpdTpdApdGpdTpdApdTpdApdCpdApdTpdGpdApdGpdGpdTpdTpdTpdGpdGpdTpdTpdGpdApdGpdApdCpdTpdApdGpdTpdCpdGpdCpdApdApdGpdApdTpdApdTpdApdGpdApdTpdApdGpdTpdApdApdGpdTpdGpdCpdApdApdTpdCpdTp-3'
96 29854.53 g/mole 961400.00 L/(mole·cm) 39.58% 1.04 31.05

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Blank et al. "Systematic Evolution of a DNA Aptamer Binding to Rat Brain Tumor Microvessels." The Journal of Biological Chemistry, >b>276(2001): 16464-16468.

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