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Apta-Index™: Liver-Specific Ligands (236) (ID# 200)

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Liver-Specific Ligands (236) (ID# 200)

Liver-Specific Ligands (236)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peptide Liver-Specific Ligands Tissue n/a nM (reported value) Selection Buffer (PBS, 1 M NaCl, and 2% Triton X-100) Wash Buffers (0.1% Sodium Borohydride, 0.1 M Phosphate Buffer) (PBS, 5% BSA, 0.1% cold water fish gelatin, and 5% normal goat serum in PBS) Incubation Buffer (PBS and 1.1% BSA-C) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. 77% liver uptake
NH2-GlnArgValLeuValLysLys-COOH
7 916.24 g/mole

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Ludtke et al. "In Vivo Selection and Validation of Liver-Specific Ligands Using a New T7 Phage Peptide Display System." Drug Delivery, 14(2007): 357-369.

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