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Apta-Index™: Rous Sarcoma Virus (A) (ID# 168)

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Rous Sarcoma Virus (A) (ID# 168)

Rous Sarcoma Virus (A)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA Rous Sarcoma Virus Cells 20 nM (reported value) Binding buffer: 2.5 mM MgCl2, 100 mM NaCl, 20 mM Tris-HCl (pH 7.4) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. Reported Kd reflects the concentration of RNA that neutralizes 85-92 percent of RSV.

Provided Kd is 3 ug/mL of RSV protein.
5'-rGprGprGprAprGpfCpfUpfCprAprGprAprApfUprAprAprApfCprGpfCpfUpfCprAprAprGprGprGpfUprAprGprGprGprApfUpfCprGpfUpfUprApfCpfCpfCpfCprGprApfCprApfUpfUpfUpfUprAprApfUprGprGprGpfCpfCprGprApfUprGpfUpfUpfUpfCprGprApfCprApfUprGprAprGprGpfCpfCpfCprGprGprApfUpfCpfCprGprGpfCp-3'
87 28169.78 g/mole 861600.00 L/(mole·cm) 55.17% 1.16 32.69

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Pan et al. Isolation of virus-neutralizing RNAs from a large pool of random sequences." PNAS, 92(1995): 11509-11513.

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