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Apta-Index™: Interleukin-17A/F (IL-17A/F) (APTAF42) (ID# 119)

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Interleukin-17A/F (IL-17A/F) (APTAF42) (ID# 119)

Interleukin-17A/F (IL-17A/F) (APTAF42)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA Human Interleukin-17A/F Protein 72.2 nM (reported value) Binding Buffer (145 mM sodium chloride, 5.4 mM potassium chloride, 0.8 mM magnesium chloride, 1.8 mM calcium chloride, 20 mM Tris–HCl (pH 7.6) supplemented with 0.05% Tween20
N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding. See also the optimized version: AptAF42dope1.
5'-rGprGprGpfCpfUprAprGpfCpfUprGprApfUpfCprGpfUprApfCpfCpfCprAprGpfUprAprGpfCprGpfUprGprGpfCprApfUprGprGprGprGpfUprGpfCpfCpfUprAprGpfUpfCprGprGprGpfCprGprApfUprApfCpfUprAprApfCprAprGpfCpfUprAprApfCprApfCpfCpfCp-3'
69 22313.31 g/mole 670800.00 L/(mole·cm) 59.42% 1.49 33.26

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Adachi, H., et al. "Antagonistic RNA aptamer specific to a heterodimeric form of human interleukin-17A/F." Biochemie, 93 (2011): 1081-1088.

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