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Apta-Index™: S-adenosyl homocysteine (CTH-5) (ID# 106)

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S-adenosyl homocysteine (CTH-5) (ID# 106)

S-adenosyl homocysteine (CTH-5)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RNA S-adenosyl homocysteine Small Organic 0.1 nM (reported value) RNA Buffer (300 mM NaCl, 25 mM Tris (pH 7.6), 5 mM MgCl2) HBS Buffer (10 mM HEPES (pH 7.4), 150 mM NaCl, 3.4 mM EDTA, and 0.005% P-20) Carbonate Buffer (0.05 M NaHCO3 0.125 M NaCl (pH 8.3)) N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rGprGprGprCprGprGprAprUprGprAprGprAprCprGprCprUprUprGprGprCprGprUprGprUprGprCprUprGprUprGprGprAprGprAprGprUprCprAprUprCprCprGp-3'
42 13669.26 g/mole 410600.00 L/(mole·cm) 64.29% 2.44 33.29

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Gebhardt, K., et al. "RNA Aptamers to S-Adenosylhomocysteine: Kinetic Properties, Divalent Cation Dependency, and Comparison with Anti-S-adenosylhomocysteine Antibody." Biochemistry, 39 (2000): 7255-7265.

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