Aptagen, LLC
DNA
Hematoporphyrin IX (HPIX)
Small Organic
1.6 µM (reported value)
Selection Buffer: 100 mM Trisƒ??acetate (pH 8.0), 200 mM sodium acetate, 50 mM potassium acetate, 25 mM magnesium acetate, 5% dioxane
RT°C
Heated to 95°C for 5 min and then slowly cooled to room temperature.
Forms a parallel G-quartet structure.
Hematoporphyrin IX (ID# 92)
5' dTpdApdGpdGpdGpdApdApdTpdTpdCp dGpdTpdCpdGpdApdCpdGpdGpdApdTp dCpdCpdCpdApdApdTpdGpdGpdGpdGp dTpdCpdGpdGpdGpdCpdGpdGpdGpdCp dCpdGpdGpdGpdTpdGpdTpdCpdApdTp dGpdGpdTpdGpdGpdApdCpdGpdGpdAp dGpdApdTpdGpdGpdGpdApdCpdGpdTp dApdGpdApdGpdGpdGpdCpdGpdGpdTp dCpdTpdGpdCpdApdGpdGpdTpdCpdGp dApdCpdGpdCpdApdTpdGpdCpdGpdCpdCpdGp 3'
109
31939.63 g/mole
986100 L/(mole·cm)
66.67%
1.01
32.39
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
A Okazawa, A Kobayashi, et al. (2000) In vitro selection of hematoporphyrin binding DNA aptamers. Bioorg Med Chem Lett. 10:2653-2656.
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