Aptagen, LLC
DNA
Human Collagen XIα1 (C-telopeptide region)
Peptide
23 +/- 5 nM (reported value)
1x PBS selection buffer
With tRNA in a 1:10 ratio with library and 1 ug/mL BSA included to increase stringency
37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Showed preferential binding to target over counter-target BSA
D1 (ID# 7274)
5'dGpdGpdTpdTpdGpdApdCpdGpdGpdCpdApdGpdTpdCpdGpdGpdCpdGpdGpdTpdApdTpdGpdCpdGpdCpdApdTpdApdTpdCpdGpdTpdGpdTpdTpdGpdGpdTpdAp3'
40
12534.09 g/mole
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Lorenzo-Gomez, R, et al. Aptamers targeting a tumor-associated extracellular matrix component: The human mature collagen XIa1. Analytica Chimica Acta, 1189 (2022): 339206. doi: https://doi.org/10.1016/j.aca.2021.339206
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