Aptagen, LLC
RNA
Epithelial cellular activating molecule (EpCAM)
Cells
39.89 nM (reported value)
PBS containing 5 mM MgCl2
25 and 37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
EP23 (ID# 7161)
5'rAprCprGprUprAprUprCprCprCprUprUprUprUprCprGprCprGprUprAp3'
19
5631.6 g/mole
165300 L/(mole·cm)
47.37%
6.05
34.07
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Bell DR, Weber JK, Yin W, Huynh T, Duan W, Zhou R. In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimers. Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8486-8493. doi: 10.1073/pnas.1913242117. Epub 2020 Mar 31. Erratum in: Proc Natl Acad Sci U S A. 2021 Feb 16;118(7): PMID: 32234785; PMCID: PMC7165443.
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